Bright Skin Days with Sesderma C-VIT 5 Serum

I’ve been chasing that glowy, even-toned skin for a while now, and Vitamin C serums are my go-to.

When I stumbled across the Sesderma C-VIT 5 Liposomal Serum, with its bold claim of five types of Vitamin C, I was intrigued. Does it really brighten, hydrate, and fight aging like it says?

Here’s my experience after using it for a month.

What Is Sesderma C-VIT 5 Liposomal Serum?

Sesderma is a Spanish skincare brand, founded in 1989 by Dr. Gabriel Serrano, known for using nanotechnology to deliver active ingredients deep into the skin.

The C-VIT 5 Liposomal Serum is their star product, a lightweight serum packed with five forms of stabilized Vitamin C (ascorbyl glucoside, sodium ascorbate, ethyl ascorbic acid, magnesium ascorbyl phosphate, and trisodium ascorbyl palmitate phosphate). It also includes heavy-hitters like hyaluronic acid, centella asiatica, and proteoglycans, which promise to hydrate, firm, and even out skin tone.

Sesderma C-VIT 5 Serum Product Package Being Held In Hand

The brand claims this serum boosts radiance, fades dark spots, and protects against free radicals. It’s marketed for all skin types, especially dull or aging skin, and comes in a 1.0 fl. oz bottle with a pipette for easy application.

You can use it morning and night, year-round, even in summer, as long as you follow with sunscreen.

My Skin and Routine

I’ve got combination skin—oily T-zone, dry cheeks—and a medium-dark tone (around NC40). My main concerns are uneven tone from old acne marks and occasional dullness, especially in winter.

My routine is simple: cleanser, toner, serum, moisturizer, and SPF in the morning; same at night but swap SPF for a heavier cream.

I slotted the C-VIT 5 Serum in after toner, using 4 drops as recommended.

First Impressions: Texture and Application

The serum comes in a sleek amber glass bottle with a pipette, which I love—no mess, no germs.

The texture is a thick, gel-like fluid, not runny like some serums. It spreads easily, and 4 drops cover my face, neck, and even a bit of my chest.

It has a faint citric scent, like a soft orange peel, which fades fast. If you’re sensitive to smells, this won’t bug you.

My skin drank it up quickly, leaving a slightly tacky feel for a minute before settling into a smooth, hydrated finish. No stickiness or greasiness, which is a win for my oily zones.

Key Ingredients: What’s Doing the Work?

This serum’s big flex is its five types of Vitamin C. Each form has a slightly different role—some are more stable, others penetrate deeper—but together, they’re meant to brighten, fight free radicals, and boost collagen.

I dug into the science a bit, and stabilized Vitamin C like ascorbyl glucoside is less irritating than pure ascorbic acid, making this gentler for sensitive skin.

  • Hyaluronic Acid: Keeps skin plump and hydrated. 
  • Centella Asiatica: Soothes and repairs, great for redness or irritation. 
  • Proteoglycans: These molecules help firm skin and retain moisture. 
  • Immediate Tightening Complex (Caesalpinia Spinosa Fruit Extract + Kappaphycus Alvarezii Extract): Gives a subtle lifting effect, which I noticed after a few uses.

The full ingredient list is long (check the box before buying if you’re picky), but I like that it’s free of harsh alcohols or parabens.

There’s a touch of fragrance, though, so keep that in mind.

How It Performs: The Good Stuff

Sesderma C-VIT 5 Serum Product Package Details Being Held In Hand

After a month, I’ve got plenty to say about how this serum holds up. Here’s what stood out:

Brightening and Even Tone

The first thing I noticed was a subtle glow. About a week in, my skin looked less dull, like I’d gotten a good night’s sleep (I hadn’t). My acne marks haven’t vanished, but they’re slightly less noticeable, especially around my cheeks. I’m hopeful another month will fade them more.

Hydration and Feel

This serum is hydrating without being heavy. My dry patches felt softer, and my T-zone didn’t get shinier than usual. It layers well under moisturizer and SPF, no pilling or weird texture. I’ve even used it with a facial steamer (inspired by a customer comment), and it made my skin feel extra plump.

Anti-Aging and Firming

I’m in my late 30s, so fine lines around my eyes are a thing. The tightening complex gives a slight firming effect—nothing dramatic, but my skin feels tauter in the morning. The antioxidant protection is harder to measure, but I like knowing it’s shielding my skin from pollution and UV damage (with SPF, of course).

Ease of Use

The pipette makes dosing a breeze, and the serum fits into my routine like it’s always been there. Morning or night, it plays nice with other products. I’ve used it under makeup, and it doesn’t mess with my foundation or BB cream.

The Not-So-Great Stuff

No product’s perfect, and this one’s got a couple quirks:

  • Pricey for the Size: At around $50–$60, the 1.0 fl. oz bottle feels small for the cost. I’m using 8 drops daily (morning and night), so it might last 6–8 weeks. Budget-conscious folks might hesitate.
  • Slow Results for Dark Spots: If you’re expecting overnight miracles for hyperpigmentation, you’ll need patience. My spots are fading, but it’s a gradual process.
  • Slight Tackiness: The tacky feeling post-application isn’t a dealbreaker, but if you hate any residue, it might bug you for a minute.

How It Compares to Other Vitamin C Serums

I’ve tried a few Vitamin C serums before, so here’s how Sesderma stacks up:

  • Vs. Drunk Elephant C-Firma Day Serum: Drunk Elephant’s is more potent (15% ascorbic acid) but can sting sensitive skin. Sesderma’s gentler and hydrating, better for daily use.
  • Vs. The Ordinary Vitamin C Suspension 23%: The Ordinary’s is thicker and grainy, with a stronger tingle. Sesderma feels luxurious and absorbs faster.
  • Vs. SkinCeuticals C E Ferulic: SkinCeuticals is the gold standard but costs a fortune ($180+). Sesderma’s a solid mid-range option with similar brightening vibes.

Sesderma’s edge is its multi-Vitamin C approach and hydrating extras like proteoglycans. It’s not the strongest for stubborn dark spots, but it’s versatile and comfy for all skin types.

My Routine Hacks

To get the most out of this serum, I tweaked my routine based on trial and error:

  • Morning: Cleanse, tone, apply 4 drops of C-VIT 5, follow with a lightweight moisturizer and SPF 50. If I’m feeling fancy, I use a jade roller to massage it in—feels amazing.
  • Night: Same steps, but I layer a richer cream after the serum for extra hydration. Once a week, I use a gentle exfoliant before the serum to help it penetrate.
  • auer- Steamer Trick: Inspired by a customer, I tried applying the serum while steaming my face. It’s not necessary, but it makes my skin feel super soft.

Who’s This For?

This serum’s a great pick if:

  • You want brighter, glowy skin without irritation.
  • You’ve got combination or aging skin and need hydration.
  • You like a serum that multitasks (brightening, firming, protecting).
  • You’re okay spending $50+ for quality skincare.

It might not be your vibe if:

  • You need fast results for deep hyperpigmentation.
  • You’re on a tight budget.
  • You hate any tackiness, even if it’s brief.

Final Verdict: Worth the Hype?

I’m pretty impressed with the Sesderma C-VIT 5 Liposomal Serum. It’s not a miracle worker, but it’s made my skin brighter, softer, and a bit firmer. The glow is real, and I love how it fits into my routine without fuss.

The price stings a bit, and I wish dark spots faded faster, but I’m happy enough to finish the bottle.

Will I repurchase? Absolutely, unless I find something cheaper that performs just as well. For now, it’s earned a spot on my bathroom shelf. If you’ve tried it or want to know more, let me know in the comments!